Scientific genius. Dr.Reed Richards's lifelong dream is close to being realized a trip to space and to the center of a cosmic storm to unlock the secrets of the human genetic code. Financed by reval-turned-billionaire-industrialist Victor Von Doom, Reed's crew for the mission includes his best friend, astronaut Ben Grimm; Susan Storm, Von Doom's director of genetic research and Reed's ex-girlfriend; and Sue's hot-headed younger brother, pilot Johnny Storm. With benefactor Von Doom in tow. The four set off for the exploration of a lifetime. But something goes terribly wrong as cosmic radiation irrevocably alters their DNA…and their future.